So far, between the Wiki, Voice Thread, iMovie, and Inspiration my favorite would have to be the latter. Inspiration, unlike all the rest, is intuitive. You just drag things around. Even if you get confused, less than two minutes later you'll figure it out. If not, your neighbor will know what to do. This time-friendliness is priceless in a classroom. Teenagers have far less patience than we do. I could only imagine the chaos that would ensue if iMovie were used. Half the class would be spent on entering subtitles for slides.
In iMovies defense, the program is probably easy once you use it more often. So, as a teacher with technology charging forward everyday, should I force myself to become a proficient user? The answer of course is yes. Students do not respond to a lecture you rehearsed over the weekend nearly as well as an iMovie you created (or VoiceThread for that matter). The Inspiration software is amazing, but I feel I'm going to have to mix it up to keep their attention. After begging and pleading with iMovie for hours, I've learned that iMovie is best left to teacher creation and hopefully student enjoyment.